High mutational load malignancies
Showing 1 - 25 of >10,000
CNS Tumor, Solid Tumor Trial in Worldwide (Nivolumab and Entinostat)
Recruiting
- CNS Tumor
- Solid Tumor
- Nivolumab and Entinostat
-
Randwick, New South Wales, Australia
- +13 more
Nov 8, 2022
Advanced Solid Tumours, Breast Cancer, Head Neck Cancer Trial in France (Durvalumab + Tremelimumab + metronomic Vinorelbine)
Active, not recruiting
- Advanced Solid Tumours
- +4 more
- Durvalumab + Tremelimumab + metronomic Vinorelbine
-
Angers, France
- +8 more
Jun 1, 2022
Barretts Esophagus With Dysplasia, Intramucosal Adenocarcinoma Trial in Chapel Hill (Study Driven Procurement of Biopsies)
Enrolling by invitation
- Barretts Esophagus With Dysplasia
- Intramucosal Adenocarcinoma
- Study Driven Procurement of Biopsies
-
Chapel Hill, North CarolinaUniversity of North Carolina at Chapel Hill
May 5, 2022
Metastatic Colorectal Cancer Trial in Milan (Temozolomide, Nivolumab, Ipilimumab)
Completed
- Metastatic Colorectal Cancer
- Temozolomide
- +2 more
-
Milan, MI, ItalyFondazione IRCCS Istituto Nazionale dei Tumori
Apr 1, 2022
Prostate Cancer, Renal Cancer, Urethral Cancer Trial in San Francisco (Copper-64 labeled Granzyme B (64Cu-GRIP B), Positron
Not yet recruiting
- Prostate Cancer
- +2 more
- Copper-64 labeled Granzyme B (64Cu-GRIP B)
- Positron Emission Tomography (PET)
-
San Francisco, CaliforniaUniversity of California, San Francisco
Jun 7, 2023
Endometrial Carcinoma, Tumor Molecular Features Screening Model Trial (open surgery, laparoscopic surgery)
Not yet recruiting
- Endometrial Carcinoma
- Tumor Molecular Features Screening Model
- open surgery
- laparoscopic surgery
- (no location specified)
Jun 7, 2023
Colorectal Tumors, Microsatellite Instability Trial in Milano, Rozzano (temozolomide (induction),, pembrolizumab (treatment))
Recruiting
- Colorectal Neoplasms
- Microsatellite Instability
- temozolomide (induction),
- pembrolizumab (treatment)
-
Milano, Italy
- +3 more
Sep 28, 2022
MDS Patients Using Sequential Peripheral Blood Samples
Recruiting
- Myelodysplastic Syndromes
-
Badalona, Barcelona, SpainJosep Carreras Leukaemia Research Institute
Mar 8, 2022
Epigenetic Age on Clinic-biological Presentation and Prognosis
Not yet recruiting
- Myeloproliferative Neoplasm
- Assessment of the epigenetic age
-
Bordeaux, FranceCHU de Bordeaux, service Hématologie Biologique
Aug 28, 2023
Metastatic Solid Tumor, SF3B1 Gene Mutation, Spliceosome Mutation Trial in Baltimore (Recommendation for treatment with
Recruiting
- Metastatic Solid Tumor
- +4 more
- Recommendation for treatment with immunotherapy
-
Baltimore, MarylandJohns Hopkins University
Sep 8, 2022
Chronic Latent EBV Infection
Recruiting
- EBV Infection
- peripheral EBV-DNA load
-
Wuhan, Hubei, ChinaTongji hospital, Tongji medical collage of HUST
Feb 9, 2021
Cardiovascular Disease Trial in Atlanta (Decoding Your Diet)
Not yet recruiting
- Cardiovascular Disease
- Decoding Your Diet
-
Atlanta, GeorgiaMorehouse School of Medicine
Jun 14, 2023
Stage IV Peritoneal Surface Dissemination From Gastrointestinal or Recurrent, Platinum-resistant Ovarian Cancer That Cannot be
Completed
- Stage IV Peritoneal Surface Dissemination From Gastrointestinal or Recurrent, Platinum-resistant Ovarian Cancer That Cannot be Completely Resected
- Talimogene Laherparepvec
-
Chicago, Illinois
- +2 more
Nov 17, 2022
Refractory Solid Organ Malignancies Trial in Singapore (DRUID AI Program)
Not yet recruiting
- Refractory Solid Organ Malignancies
- DRUID AI Program
-
Singapore, SingaporeDepartment of Hematology-Oncology, National University Hospital
Jan 30, 2023
Pediatric Cancer Trial (Nivolumab)
Approved for marketing
- Pediatric Cancer
- Nivolumab
- (no location specified)
Nov 17, 2021
Genome Instability, Genetic Predisposition to Disease, Gene Rearrangement Trial in Rome (Diagnostic Test)
Recruiting
- Genome Instability
- +2 more
- Diagnostic Test
-
Rome, ItalyFondazione Policlinico Universitario Agostino Gemelli IRCCS
Aug 30, 2023
Prospective Sinonasal Cancer Multi-institution Study
Recruiting
- Sinonasal Carcinoma
-
Rochester, MinnesotaMayo Clinic in Rochester
Feb 15, 2022
NSCLC, Urothelial Cancer Trial in Worldwide (Avelumab 800 mg in combination with pemetrexed / carboplatin, Avelumab 800 mg in
Active, not recruiting
- Non-small Cell Lung Cancer
- Urothelial Cancer
- Avelumab 800 mg in combination with pemetrexed / carboplatin
- +3 more
-
Tucson, Arizona
- +45 more
Oct 13, 2022
Oncogenic Drivers and Somatic Evolution in the Oral Mucosa
Not yet recruiting
- Carcinoma, Squamous Cell
- Oral cytobrush
-
Bougival, France
- +14 more
Oct 16, 2023
Ovarian Epithelial Cancer, Carcinoma in Situ, Ovarian Cancer Trial in Worldwide (Speiser-catheter for uterine and tubal lavage)
Completed
- Ovarian Epithelial Cancer
- +2 more
- Speiser-catheter for uterine and tubal lavage
-
Graz, Austria
- +8 more
Sep 1, 2022
Fertility Issues Trial in New York, Portland, Kirkland (Embryo genome sequencing, Parents genome sequencing)
Not yet recruiting
- Fertility Issues
- Embryo genome sequencing
- Parents genome sequencing
-
New York, New York
- +2 more
Feb 13, 2023
Mucositis Oral Trial in Izmir (oral self care protocol, standard care)
Completed
- Mucositis Oral
- oral self care protocol
- standard care
-
İzmir, Bornova, TurkeyEge University Medical Faculty Hospital
Sep 21, 2023
A New Mutational and Epigenetic Signature to Predict Early OPSCC
Recruiting
- Oropharyngeal Squamous Cell Carcinoma
-
Aviano, Italy
- +4 more
Nov 14, 2023
Tumor Mutational Burden in Lung Cancer Patients
Terminated
- Non Small Cell Lung Cancer
- +3 more
- TMB assessment
-
Clermont-Ferrand, Auvergne-Rhône-Alpes, France
- +7 more
Jun 23, 2021